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The drug is still associated with a lower liver cancer rate than Baraclude.
A quick overview of Hep Magazine’s reporting on the 53rd International Liver Congress in Vienna
People who took Viread were about two thirds less likely to develop HCC, but this could be related to other factors as well.
People who added ABI-H0731 saw greater viral load reductions than those who used nucleoside/nucleotide analogues alone.
Researchers analyzed a cohort of South Koreans taking Viread (tenofovir disoproxil fumarate) or Baraclude (entecavir) for hepatitis B.
This includes a higher risk of liver cancer, cirrhosis-related complications and death.
The exception is those people with hepatitis B and liver cancer.
However, no such difference was seen among those with cirrhosis or those whose virus was not well treated.
Low but detectable HBV DNA during antiviral therapy is associated with detrimental long-term outcomes.
Such generic drugs could save nations huge sums in the coming years.
Treatment with Viread and Baraclude led to a decline in liver cancer in Europe but not in South Korea.
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