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One in five counties had an increase in deaths from hepatitis C, even as the nation experienced a general decline in mortality rates.
The decrease is largely due to improved lung cancer treatment, but the impact of COVID-19 is not yet known.
The hep C mortality reduction goal will not be met by any state, according to recent projections.
All-cause mortality rates were highest among those with NAFLD-related cirrhosis.
Researchers found that more than 700,000 fewer people would die if the per capita coffee consumption were four or more cups per day.
Only three states are expected to meet the 2030 goal.
Liver complications, heart disease and non-liver cancers also account for most deaths among people with hepatitis B or C.
Coinfection with all three viruses ramped up mortality risk nine times compared with having none of the viruses.
NAFLD is the leading indicator of mortality among Medicare beneficiaries with hepatocellular carcinoma.
A fifth of the worldwide population with fatty liver disease consists of lean people.
Exercising for a longer period of time was especially linked to a reduced risk of death from cardiovascular conditions.
However, people with cirrhosis alone were as likely to die as those with both cirrhosis and COVID-19.
Cancer mortality fell by 29% between 1991 and 2017, largely driven by a decline in lung cancer deaths.
HCV-related mortality in the country fell by more than 16 percent over the past two years.
Cancer mortality declined by 27 percent over the past 25 years.
Liver cancer rates and deaths have doubled in the United States, Canada, Australia and United Kingdom.
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