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A placebo-controlled study of obeticholic acid showed it improved liver fibrosis with no worsening of non-alcoholic steatohepatitis.
The placebo-controlled trial Phase III trial of selonsertib had sought to improve fibrosis while not worsening NASH.
In an analysis of the liver health of a cohort of HIV/hep B–coinfected people, one third had significant fibrosis.
Researchers believe this genetic mutation protected against the 14th century-bubonic plague.
Direct-acting antivirals lower this risk to a greater extent than interferon-based regimens.
This is according to the large randomized controlled START trial.
Those with greater fibrosis before treating hep C see the greatest benefit.
Damage to the liver can be caused by many factors, such as the hepatitis virus. What is the difference between fibrosis and cirrhosis?
AZT and ddI were the main drugs associated with liver damage in a new study.
This finding applies to those who begin treatment with progressive liver fibrosis, or scarring.
Additionally, among those with non-alcoholic fatty liver disease, indicators of liver fibrosis are associated with cancer.
Multiple studies have reached this conclusion, raising concerns about sexually transmitted hep C among gay and bi men who have HIV.
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