Nucleotide NS5B Polymerase Inhibitors
*generic version available
|GENERIC NAME sofosbuvir|
|COMPANY Gilead Sciences|
What are Nucleotide NS5B Polymerase Inhibitors?
These drugs block the NS5B protein, which plays a role in the replication of HCV and is involved in creating copies of the viral RNA genome. Sovaldi is used to treat HCV genotypes 1, 2, 3 and 4 and is part of a once-a-day combination pill with the NS5A inhibitor ledipasvir. Sovaldi may also be combined with other drugs, such as Daklinza, Olysio, or ribavirin, depending on various factors.