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Multi-Class Combination Drugs

Multi-class combination drugs are a combination of drugs formulated into a single pill or package of pills. For instance, the drug Harvoni combines two drugs, ledipasvir and sofosbuvir. Ledipasvir is an NS5A inhibitor and is only sold as part of Harvoni or its generic equivalent; sofosbuvir may be prescribed separately under the brand name of Sovaldi.

*generic or biosimilar available

E experimental


DRUG Epclusa*
Epclusa
GENERIC NAME sofosbuvir/velpatasvir
COMPANY Gilead Sciences
DRUG Harvoni*
GENERIC NAME ledipasvir/sofosbuvir
COMPANY Gilead Sciences
DRUG Mavyret
GENERIC NAME glecaprevir + pibrentasvir
COMPANY AbbVie
DRUG Vosevi
GENERIC NAME sofosbuvir/velpatasvir/voxilaprevir
COMPANY Gilead Sciences
DRUG Zepatier
GENERIC NAME elbasvir/grazoprevir
COMPANY Merck
DRUG daclatasvir + asunaprevir + beclabuvir
GENERIC NAME daclatasvir/asunaprevir/beclabuvir
COMPANY Bristol-Myers Squibb

Last Reviewed: March 7, 2019


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